It's really not hard. The best way to do it is get into a really, and I mean REALLY bad mood. Then as you are looking at the beautiful stuffed animal lovingly given to your daughter 4 years ago when she was 2 you can say, "Oh to Hell with it. She doesn't play with it" and chuck that bad boy into the trash. It helps also to be packing the things that belong to the child or spouse who has most recently pissed you off. Swear to God, you can get it done in an hour or so. Right now I could pack up Connor and Sasha and have no real proof of their exsistence in a matter of minutes.
Easy Peasy.
Now, people you like or stuff you care about...well....that can take a while.